購物車
幫助
021-54845833/15800441009
中文名稱：ASB2抗原（重組蛋白）
英文名稱： ASB2 Antigen (Recombinant Protein)
別 名： ASB-2
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 340-535 amino acids of human ASB2 |
|
Full name: |
ankyrin repeat and SOCS box containing 2 |
|
Synonyms: |
ASB-2 |
|
Swissprot: |
Q96Q27 |
|
Gene Accession: |
BC032354 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
