購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Full name: |
Kruppel-like factor 11 |
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Synonyms: |
FKLF; FKLF1; MODY7; TIEG2; Tieg3 |
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Swissprot: |
O14901 |
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Gene Accession: |
BC063286 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. |
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