購物車
幫助
021-54845833/15800441009
中文名稱：ILK抗原（重組蛋白）
英文名稱： ILK Antigen (Recombinant Protein)
別 名： P59; ILK-1; ILK-2; p59ILK
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 193-446 amino acids of human ILK |
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Full name: |
integrin-linked kinase |
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Synonyms: |
P59; ILK-1; ILK-2; p59ILK |
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Swissprot: |
Q13418 |
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Gene Accession: |
BC001554 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. |
