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中文名稱：兔抗DFFB多克隆抗體

英文名稱： Anti-DFFB rabbit polyclonal antibody

別名： CAD; CPAN; DFF2; DFF40; DFF-40

相關類別：一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： DFFB

反應種屬： Human, Mouse, Rat

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規(guī)格

Background:

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined.

Applications:

ELISA, IHC

Name of antibody:

DFFB

Immunogen:

Synthetic peptide of human DFFB

Full name:

DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)

Synonyms：

CAD; CPAN; DFF2; DFF40; DFF-40

SwissProt:

O76075

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

25-100

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ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎培養(yǎng)基

完全培養(yǎng)基

原代細胞

細胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

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兔抗DFFB多克隆抗體

Background:	Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined.
Applications:	ELISA, IHC
Name of antibody:	DFFB
Immunogen:	Synthetic peptide of human DFFB
Full name:	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
Synonyms：	CAD; CPAN; DFF2; DFF40; DFF-40
SwissProt:	O76075
ELISA Recommended dilution:	1000-5000
IHC positive control:	Human esophagus cancer
IHC Recommend dilution:	25-100