国产精品人人做人人爽人人添,国产日本一区二区精品

中文名稱：兔抗EPHB1/2/3 多克隆抗體

英文名稱： Anti-EPHB1/2/3 rabbit polyclonal antibody

別名： ELK; NET; Hek6; EPHT2/DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5/ETK2; HEK2; TYRO6

抗原： EPHB1/2/3

儲(chǔ) 存： 冷凍（-20℃）避光

宿主： Rabbit

反應(yīng)種屬： Human Mouse

相關(guān)類別： 一抗

標(biāo) 記物： Unconjugate

克隆類型： Unconjugate

技術(shù)規(guī)格

Background:

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.

Applications:

IHC, IF

Name of antibody:

EPHB1/2/3

Immunogen:

Synthesized peptide derived from internal of human EPHB1/2/3.

Full name:

EPH receptor B1/2/3

Synonyms：

ELK; NET; Hek6; EPHT2/DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5/ETK2; HEK2; TYRO6

SwissProt:

P54762/P29323/P54753

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

IF positive control:

NIH/3T3 cells

IF Recommend dilution:

100-500

展開(kāi)全部

兔抗EPHB1/2/3 多克隆抗體說(shuō)明書(shū)
下載

欧洲亚洲国产成人综合色婷婷|成人欧美一区二区三区的电影|高潮毛片无遮挡高清视频播放|亚洲一线二线三线品牌久久久

021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標(biāo)準(zhǔn)品

血清

產(chǎn)品中心

最新產(chǎn)品

相關(guān)文章

兔抗EPHB1/2/3 多克隆抗體

Background:	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
Applications:	IHC, IF
Name of antibody:	EPHB1/2/3
Immunogen:	Synthesized peptide derived from internal of human EPHB1/2/3.
Full name:	EPH receptor B1/2/3
Synonyms：	ELK; NET; Hek6; EPHT2/DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5/ETK2; HEK2; TYRO6
SwissProt:	P54762/P29323/P54753
IHC positive control:	Human brain tissue
IHC Recommend dilution:	50-100
IF positive control:	NIH/3T3 cells
IF Recommend dilution:	100-500