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中文名稱: 兔抗EWSR1多克隆抗體

英文名稱: Anti-EWSR1 rabbit polyclonal antibody

別名: EWS RNA binding protein 1; EWS; EWS-FLI1; bK984G1.4

抗原: EWSR1

儲(chǔ) 存: 冷凍（-20℃）

宿主: Rabbit

反應(yīng)種屬: Human, Mouse

相關(guān)類別: 一抗

標(biāo) 記物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Applications:

ELISA, WB, IHC

Name of antibody:

EWSR1

Immunogen:

Fusion protein of human EWSR1

Full name:

EWS RNA binding protein 1

Synonyms:

EWS; EWS-FLI1; bK984G1.4

SwissProt:

Q01844

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer and Human esophagus cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

68 kDa

WB Positive control:

K562 and HepG2 cell lysates

WB Recommended dilution:

1000-5000

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兔抗EWSR1多克隆抗體說(shuō)明書
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生化試劑盒

細(xì)胞系

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原代細(xì)胞

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菌株

生化試劑

病理染色液

科研抗體

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兔抗EWSR1多克隆抗體

Background:	This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
Applications:	ELISA, WB, IHC
Name of antibody:	EWSR1
Immunogen:	Fusion protein of human EWSR1
Full name:	EWS RNA binding protein 1
Synonyms:	EWS; EWS-FLI1; bK984G1.4
SwissProt:	Q01844
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human breast cancer and Human esophagus cancer
IHC Recommend dilution:	50-300
WB Predicted band size:	68 kDa
WB Positive control:	K562 and HepG2 cell lysates
WB Recommended dilution:	1000-5000