購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： UBXN1 抗原（重組蛋白）
英文名稱： UBXN1 Antigen (Recombinant Protein)
別 名： UBX domain protein 1; 2B28; SAKS1; UBXD10
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述
|
Full name: |
UBX domain protein 1 |
|
Synonyms: |
2B28; SAKS1; UBXD10 |
|
Swissprot: |
Q04323 |
|
Gene Accession: |
BC001372 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. |
