購物車
幫助
021-54845833/15800441009
中文名稱：兔抗S100B多克隆抗體
英文名稱： Anti-S100B rabbit polyclonal antibody
別 名： NEF; S100; S100-B; S100beta
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
抗 原： S100B
宿 主： Rabbit
反應種屬： Human, Mouse, Rat
標記物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
S100B |
|
Immunogen: |
Synthetic peptide of human S100B |
|
Full name: |
S100 calcium binding protein B |
|
Synonyms： |
NEF; S100; S100-B; S100beta |
|
SwissProt: |
P04271 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human brain |
|
IHC Recommend dilution: |
25-100 |
