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  • 兔抗SLC8A1多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW21353
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:90
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中文名稱:兔抗SLC8A1多克隆抗體  

英文名稱: Anti-SLC8A1 rabbit polyclonal antibody

別      名: NCX1

相關類別: 一抗

儲      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: SLC8A1

反應種屬: Human, Mouse, Rat

標記物 Unconjugate

克隆類型: rabbit polyclonal


技術規(guī)格

Background:

In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.

Applications:

ELISA, IHC

Name of antibody:

SLC8A1

Immunogen:

Synthetic peptide of human SLC8A1

Full name:

solute carrier family 8 (sodium/calcium exchanger), member 1

Synonyms:

NCX1

SwissProt:

P32418

ELISA Recommended dilution:

500-1000

IHC positive control:

Human brain and human tonsil

IHC Recommend dilution:

25-100




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