購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FOXN1 |
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Immunogen: |
Synthetic peptide of human FOXN1 |
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Full name: |
forkhead box N1 |
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Synonyms： |
WHN, RONU, FKHL20 |
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SwissProt: |
O15353 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
25-100 |
