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中文名稱：兔抗FOXO1 (Phospho-Ser319)多克隆抗體

英文名稱： Anti-FOXO1 (Phospho-Ser319) rabbit polyclonal antibody

別名： FKH1; FKHR; FOXO1A

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： FOXO1 (Phospho-Ser319)

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14

Applications:

WB, IHC, IF

Name of antibody:

FOXO1 (Phospho-Ser319)

Immunogen:

Synthetic peptide of human FOXO1 (Phospho-Ser319)

Full name:

forkhead box O1 (Phospho-Ser319)

Synonyms：

FKH1; FKHR; FOXO1A

SwissProt:

Q12778

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

70 kDa

WB Positive control:

NIH/3T3 cells untreated or treated with serum starvation

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200

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兔抗FOXO1(Phospho-Ser319)多克隆抗體說(shuō)明書(shū)
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兔抗FOXO1(Phospho-Ser319)多克隆抗體

Background:	FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14
Applications:	WB, IHC, IF
Name of antibody:	FOXO1 (Phospho-Ser319)
Immunogen:	Synthetic peptide of human FOXO1 (Phospho-Ser319)
Full name:	forkhead box O1 (Phospho-Ser319)
Synonyms：	FKH1; FKHR; FOXO1A
SwissProt:	Q12778
IHC positive control:	Human breast carcinoma
IHC Recommend dilution:	50-100
WB Predicted band size:	70 kDa
WB Positive control:	NIH/3T3 cells untreated or treated with serum starvation
WB Recommended dilution:	500-1000
IF Positive control:	Hela cells
IF Recommended dilution	100-200