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中文名稱：兔抗FOXO3多克隆抗體

英文名稱： Anti-FOXO3 rabbit polyclonal antibody

別名： FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： FOXO3

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. Interacts with YWHAB/14-3-3-beta and YWHAZ/14-3-3-zeta, which are required for cytosolic sequestration. Upon oxidative stress, interacts with STK4/MST1, which disrupts interaction with YWHAB/14-3-3-beta and leads to nuclear translocation. Interacts with PIM1. Interacts with DDIT3/CHOP.

Applications:

ELISA, IHC

Name of antibody:

FOXO3

Immunogen:

Synthetic peptide of human FOXO3

Full name:

forkhead box O3

Synonyms：

FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2

SwissProt:

O43524

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

50-150

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兔抗FOXO3多克隆抗體說明書
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菌株

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病理染色液

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兔抗FOXO3多克隆抗體

Background:	This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. Interacts with YWHAB/14-3-3-beta and YWHAZ/14-3-3-zeta, which are required for cytosolic sequestration. Upon oxidative stress, interacts with STK4/MST1, which disrupts interaction with YWHAB/14-3-3-beta and leads to nuclear translocation. Interacts with PIM1. Interacts with DDIT3/CHOP.
Applications:	ELISA, IHC
Name of antibody:	FOXO3
Immunogen:	Synthetic peptide of human FOXO3
Full name:	forkhead box O3
Synonyms：	FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2
SwissProt:	O43524
ELISA Recommended dilution:	1000-5000
IHC positive control:	Human cervical cancer
IHC Recommend dilution:	50-150