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中文名稱： 兔抗PGRMC2多克隆抗體
英文名稱： Anti-PGRMC2 rabbit polyclonal antibody
別 名： DG6; PMBP
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PGRMC2
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PGRMC2 |
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Immunogen: |
Fusion protein of human PGRMC2 |
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Full name: |
progesterone receptor membrane component 2 |
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Synonyms: |
DG6; PMBP |
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SwissProt: |
O15173 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and Human tonsil |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
24 kDa |
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WB Positive control: |
RAW264.7 and NIH/3T3 cell lysates |
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WB Recommended dilution: |
500-2000 |
