購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PLAUR多克隆抗體
英文名稱： Anti-PLAUR rabbit polyclonal antibody
別 名： CD87; UPAR; URKR; U-PAR
抗 原： PLAUR
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human
標(biāo) 記 物 ： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PLAUR |
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Immunogen: |
Fusion protein of human PLAUR |
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Full name: |
Plasminogen activator, urokinase receptor |
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Synonyms： |
CD87; UPAR; URKR; U-PAR |
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SwissProt: |
Q03405 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human lung cancer and Human colon cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
37 kDa |
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WB Positive control: |
A549 cells |
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WB Recommended dilution: |
500-2000 |
