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中文名稱：兔抗TEAD2多克隆抗體

英文名稱： Anti-TEAD2 rabbit polyclonal antibody

別名： TEA domain transcription factor 2; ETF; TEF4; TEF-4; TEAD-2

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

抗原： TEAD2

宿主： Rabbit

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

Applications:

ELISA, IHC

Name of antibody:

TEAD2

Immunogen:

Fusion protein of human TEAD2

Full name:

TEA domain transcription factor 2

Synonyms:

ETF; TEF4; TEF-4; TEAD-2

SwissProt:

Q15562

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

40-200

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兔抗TEAD2多克隆抗體

Background:	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
Applications:	ELISA, IHC
Name of antibody:	TEAD2
Immunogen:	Fusion protein of human TEAD2
Full name:	TEA domain transcription factor 2
Synonyms:	ETF; TEF4; TEF-4; TEAD-2
SwissProt:	Q15562
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human gastric cancer
IHC Recommend dilution:	40-200