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中文名稱：兔抗TERT多克隆抗體

英文名稱： Anti-TERT rabbit polyclonal antibody

別名： TP2; TRT; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1

相關(guān)類別：一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： TERT

反應(yīng)種屬： Human

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

Applications:

ELISA, IHC

Name of antibody:

TERT

Immunogen:

Synthetic peptide of human TERT

Full name:

telomerase reverse transcriptase

Synonyms：

TP2; TRT; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1

SwissProt:

O14746

ELISA Recommended dilution:

3000-10000

IHC positive control:

Human tonsil and Human esophagus cancer

IHC Recommend dilution:

50-200

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兔抗TERT多克隆抗體

Background:	Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
Applications:	ELISA, IHC
Name of antibody:	TERT
Immunogen:	Synthetic peptide of human TERT
Full name:	telomerase reverse transcriptase
Synonyms：	TP2; TRT; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1
SwissProt:	O14746
ELISA Recommended dilution:	3000-10000
IHC positive control:	Human tonsil and Human esophagus cancer
IHC Recommend dilution:	50-200