購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗CDKN2AIP多克隆抗體
英文名稱： Anti-CDKN2AIP rabbit polyclonal antibody
別 名： CARF
抗 原： CDKN2AIP
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
CDKN2AIP |
|
Immunogen: |
Fusion protein of human CDKN2AIP |
|
Full name: |
CDKN2A interacting protein |
|
Synonyms： |
CARF |
|
SwissProt: |
Q9NXV6 |
|
ELISA Recommended dilution: |
1000-5000 |
|
IHC positive control: |
Human thyroid cancer |
|
IHC Recommend dilution: |
50-200 |
