購(gòu)物車
幫助
021-54845833/15800441009
別 名： MUM1; LSIRF; SHEP8; NF-EM5
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
IRF4 |
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Immunogen: |
Fusion protein of human IRF4 |
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Full name: |
interferon regulatory factor 4 |
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Synonyms: |
MUM1; LSIRF; SHEP8; NF-EM5 |
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SwissProt: |
Q15306 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain and human lung cancer |
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IHC Recommend dilution: |
30-150 |
